Adaptive Designs in Clinical TrialsDates:   8th– 9thApril 2013Venue: London, England The expert speakers at the 8thannual Adaptive Designs in Clinical Trials – the only conference in Europe to focus specifically on adaptive designs – are widely regarded as industry leaders.  Through their first-hand accounts and in-depth case studies you will learn how to quickly and accurately implement an adaptive design clinical trial for your drug development from initial processes in managing trials to choosing the right time to implement change.  Key topics include: The motivation, promise, and success of Bayesian adaptive trial designAn adaptive design to explore prevention therapies for Alzheimer's DiseaseControlling the weighted sum of Type I and Type II errors, and implications for the design and analysis of adaptive designsFrom preclinical studies to adaptive designs – a path to the futureBayesian Variable Selection (BVS) approach for dose-response modellingAdaptive sample size and modification in clinical trials: start small then ask for more?Adaptive trials in pre-clinical discoveryPaediatric adaptation: early (stage) we practice, later perhaps we practice lessDesigning multi-arm multi-stage clinical trialsExploratory dose finding in malaria Speakers include:Andy Kenwright, Project Statistician, Roche Products Emmanuel Pham, Senior Director Global R&D Statistics, IpsenVladimir Anisimov, Senior Strategic Biostatistics Director, QuintilesChristopher Jennison, Professor of Statistics, University of BathFrank Fleischer, Teamleader Clinical Biostatistics, Boehringer-IngelheimMicheal Krams, VP – Head of Neurology Franchise, Johnson & JohnsonThomas Jaki, Researcher, Department of Mathematics and Statistics, Lancaster UniversityMartin Simán, Director, AstraZenecaJouni Kerman, Statistical Methodologist, NovartisAlun Bedding, Director, Biostatistics and Programming Development Partners, GlazoSmithKlineand more . . .