As in previous editions Nanoschool 2014 is promoted with two distinct initiatives: the Nanoschool Course, entitled “Nanomedicines: Considerations for Design and Transfer into Clinical Use”, for registered participants, and the Nanoschool Conference, entitled "Nanomedicines: Fact of Fiction?", open for the public in general.NANOSCHOOL COURSETitle: "Nanomedicines: Considerations for Design and Transfer into Clinical Use". Dates: 6th, 7th and 9th October 2014, from 15h00-17h00;  8th October 2014, from 14h30-16h30. Venue: room 0.57, level 0 (University of Madeira, Campus of Penteada). Program:LESSON #01  MONDAY, 6TH What is nanomedicine and why do we need it?  Current Status of Nanomedicines in Clinical Use and Clinical Trial: Examples of Rationale for Design. Future Opportunities?LESSON #02  TUESDAY, 7THBiological Barriers, Endocytosis and Intracellular Trafficking - Key Players that Determine Nanomedicine Performance - Safety and Efficacy. What are the Future Opportunities for Improved Nanomedicine Design?LESSON #03  WEDNESDAY, 8TH Designing Polymer Therapeutics as Anticancer Nanomedicines: Choice of the Polymer/Nanomaterial, the Drug, the Targeting Residue (± Imaging Agent), Considerations During Translation. How can we better Select Patients Most Likely to Respond To Nanomedicine Therapy? Opportunities for Design  as Treatments for Other DiseasesLESSON #04  THURSDAY, 9TH Translation of Nanomedicines from Lab to Clinical Practice: Nanotoxicology, Nanomedicines Regulation, and Ethical Considerations (Are Nanomaterials Safe or Dangerous?)