SMi is pleased to present the return of their 12th annual Paediatric Clinical Trials Conference taking place on 19th – 20th March 2018, London, UK.

Clinical trials in paediatric populations still pose several challenges and often many studies remain un- published. 10 years on from the introduction of EU Paediatric Investigation Plans (PIPs) there are still many lessons to be learned about the planning and execution of trials which should be tailored around the needs of ;Recent advancements in immuno-oncology research has led to an increase in clinical trials to treat cancer in children and adolescents. Greater emphasis has also been placed on pain-free administration of drugs in the bid to increase vaccination uptake and access to medicines.

Join us as we discuss current clinical trials and the innovative digital technology being used to improve clinical recruitment and retention as well as improve the quality of data being collected. leading industry experts will be looking at how to work within regulations and foster the involvement of young people in their care. We will also be looking at the planning and executing a paediatric clinical trial and the ways this can vary according to region. We will be exploring the complexities of paediatric drug formulation and helping you determine clinical ;

Reasons to attend Paediatric Clinical Trials 2018

• Regulatory keynote from the MHRA - The UK's Early Access to Medicines Scheme (EAMS) and how this scheme benefits paediatric patients
• Hear from Amgen and Roche as they give exclusive case studies on new approaches to recruitment, retention, and clinical trial design for rare diseases
• Pfizer and Barcelona Children’s Hospital will be exploring how advancements in technology are facilitating improved clinical trials and data collection for paediatric drug development
• AstraZeneca will be reviewing and discussing paediatric clinical trial Legislation in the EU and US.
• There will be an exciting panel with the likes of GSK, Roche and regulatory bodies debating challenges and opportunities 10 years on from paediatric regulation in the EU and potential changes on the horizon
• There will be multiple pharmaceutical companies (UCB, Sanofi and GSK) debating scenarios where data extrapolation and government incentives might increase access to medicines in paediatric populations.
• Discover how to optimise your approach to clinical success through global collaboration being discussed by Takeda

CHAIRS FOR 2018:

• Mark Turner, Chair European Network of Paediatric Research, Senior Lecturer in Neonatal Medicine, European Medicines Agency and University of Liverpool
• Philippe Auby, CEO & President, OEDC, Otsuka Europe

KEYNOTE SPEAKERS INCLUDE:

• Dominik Karres, Medical Assessor, Biologicals Unit, MHRA
• Maria Zambon, Deputy Director National Infection Service, Public Health England
• Claudio Fracasso, Global Paediatric Medical Director, Pfizer

• Trupti Dixit, Director, Strategy and Operations, Takeda
• Gerhard Zugmaier, Executive Medical Director Global Development, Amgen Research
• Meghan Thorne-Miller, Project Leader and Discovery Scientist, Rare Diseases, Roche
• Amy Cheung, Senior Clinical Pharmacometrician, Project Manager, Paediatric Working Group, AstraZeneca