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Mechanisms of Recombination 2018

Topics: Recombination mechanisms​ - Links between replication and recombination - Maintenance of genome stability - Chromosome interactions and meiosis

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Summary:  Genetic recombination provides an important mechanism for the repair of chromosome breaks caused by DNA damage or replication fork demise. Defects in the recombination process have been linked to cancer predisposition, in particular breast cancers caused by mutations in BRCA1, BRCA2 and PALB2, and also acute leukemias associated with the rare genetic disease Fanconi anemia. Understanding precisely how recombination occurs is of interest to workers in the fields of meiosis, DNA repair, replication, chromosome architecture and interactions, and chromatin biology.

When

20 May 2018 @ 09:00 am

22 May 2018 @ 07:00 pm

Duration: 2 days, 10 hours


Where

Francis Crick Institute

1 Midland Road

NW1 1AT London

United Kingdom


Organised by

Abcam

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