The Asia-Pacific Conference on Life Science and Engineering(APCLSE 2014) will be held in Sanya, Hainan Island, China during February 21-23, 2014. The aim objective is to provide a platform for researchers, engineers, academicians as well as industrial professionals from all over the world to present their research results and development activities in Networking and Digital Society. This conference provides opportunities for the delegates to exchange new ideas and application experiences face to face, to establish business or research relations and to find global partners for future collaboration.All the submitted papers in these proceedings have been peer reviewed by at least two reviewers drawn from the chairs of committees depending on the subject matter of the paper. Reviewing and initial selection were undertaken electronically. A joint committee meeting was held to resolve the final paper selection and a draft programme for the conference.