Special Issue on E-Health Systems and Semantic Web Guest Editors Atilla Elçi, Aksaray University, TurkeyDuygu Çelik, Istanbul Aydin University, Turkey Description The IEEE International Workshop Series on Engineering Semantic Agent Systems (ESAS) has been held since 2006 in conjunction with Annual IEEE International Computer Software and Applications Conferences (COMPSAC). Beginning 2006, COMPSAC is designated as the IEEE Computer Society Signature Conference on Software Technology and Applications.ESAS 2015 Workshop has the following complementary objectives:Inquiring into the theory and practice of engineering semantic e-health systems, especially methods, means, and best cases;Exploring into unifying software engineering methodologies employed in implementing semantic applications across domains; and,Deploying new technologies in the fields of semantic intelligence, e-health systems, m-health systems and applications especially for distributed healthcare systems.Semantic web technologies render dynamic, heterogeneous, distributed, shared content equally accessible to human reader and software agents. Here the vision is to achieve a synergy with multi-agent technologies that other workshops have so far missed, whereby both semantics and agents will be in the center stage. ESAS 2015 Workshop aims at garnering the synergy of both technologies by taking up both the semantic web and the agent aspects of the common research issue in relation to E-health Systems.Subject Coverage Recent developments in big data, wearable sensors, mobile and semantic technologies are significantly impacting daily lives of people through people-centric systems extending human capabilities in obtaining, consuming and sharing personal information. Therefore the topics of interest span both theory and practice in big data, analytics, semantics and agents for e-health systems. Topics include, but are not limited to, the following: Smart e-health systems through web technologiesAutonomic analysis, monitoring and situation alertnessBody sensor networks and wearable sensor systems on e-healthMedical biofeedbackMedical decision support systems and toolsContext awareness and autonomous computing for ambient assisted livingE-health oriented software architectures (Agent, SOA, Middleware, etc...)E-health virtual and augmented realityEmerging e-health applicationsHealth grid and health cloudHealth monitoring and traffic classificationHealthcare management systemsICT-enabled personal health systemImage and video processing on e-healthE-health devices and smart parts for healthcare systemsE-health big data: access, aggregation and useSemantic Web rule languages and e-health systemsOntology engineering and inference on e-health systemsSemantic processing in e-healthCase studies