Manufacturing execution systems play an essential role in achieving sustainable competitive advantages in the life science industry today. As market pressures push the pharmaceutical industry to improve product quality, reduce costs and improve efficiencies, Manufacturing Execution Systems (MES) enable pharmaceutical & biotech manufacturers to respond by providing the layer for direct execution of production orders so that they can react dynamically to changing situations in orders, machine states, quality checks and more. In addition, they provide valuable real-time information on requirement changes. And they are an important prerequisite for digitization and Pharma