The 1st International Diabetes and Obesity Forum will be held in Athens, Greece, on October 21-23, 2010 and eminent guest speakers have been invited to present and review interesting and breaking through issues in the field of diabetes, obesity and other related metabolic disorders.The prevalence of diabetes and obesity, as well as of their complications, have risen considerably worldwide affecting this way the quality of life for millions of people in the planet. Taking into consideration that cardiovascular disease is dramatically on the rise in the adult population and that in the same time we experience the onset of childhood type 2 diabetes, hypertension and dyslipidaemia, it is more than obvious that metabolic disorders have become a health threat for the entire population.The scientific programme of the IDOF 2010 has been structured in such a way that covers all the critical aspects both in basic and in clinical research, including topics such as "fatty acids, metabolism and toxicity", "beta-cell function, failure and protection", "adipose tissue clinical implications", "successful diabetes and obesity management" and many more. Apart from the numerous plenary lectures, review sessions, debates, oral communications and sponsored symposia that have been integrated in the programme, innovative ways of communication with interactive sessions and vivid exchange of knowledge will be established introducing the transition from congress to forum.The IDOF 2010 aspires to bring the latest evolution in the field to all health professionals involved in the treatment of diabetes, obesity and their complications, aiming to a more comprehensive every day practice.